Sleep Disturbance in Glaucoma Patients Due To Retinal Ganglion Cell Death
In a Medical Research interview, Carolina P B Gracitelli, MD, discusses a study that suggests sleep disturbances in glaucoma patients should be incorporated into clinical evaluations.
Medical Research: What should clinicians and patients take away from your report?
Dr. Gracitelli: Our data support the concept that glaucoma is associated with a loss of ipRGCs that mediate the pupillary light response, particularly to the sustained component of the blue flash with a luminance of 250 cd/m2. Additionally, glaucoma patients had significant sleep disturbances that were inversely correlated with a measure of ipRGC function, the pupillary light reflex. These results suggest that the loss of ipRGCs in glaucoma may also lead to sleep disturbances. Both non-visual functions of ipRGCs are correlated, indicating that attention should be paid to the non-image forming visual functions in glaucoma patients.